Shijiazhuang kidney hospital how to treat lupus nephritis

Sore nephritis (LN) is a systemic lupus erythematosus (SLE) involving an immune complex glomerulonephritis caused kidney medicine course of the disease in remission and minds characterized by alternating episodes of acute visceral (kidney
CNS) damage prognosis compared particularly poor. Lupus nephritis is more common in the acute phase of fever; the majority of patients with anemia; facial butterfly erythema characteristic changes. Be accompanied by joint swelling, hair loss, skin rashes, heart murmur or pericardial effusion, hepatosplenomegaly, lymphadenopathy, and varying degrees of edema or pleural effusion and so on.

 (1)Shijiazhuang Kidney Disease Hospital long-term treatment of lupus nephritis. The disease has a strong genetic background, medication can be a good date to alleviate the condition, but not completely effective treatment, it requires long-term medication.

 (2) according to the degree of disease activity stage treatment. When lupus is active, the kidney inflammation is severe, often require large doses of several drugs in combination therapy (such as hormones, Xiao interest, etc.) (referred to as induction therapy) is designed to quickly control the inflammation and prevent kidney damage continues to increase .

 (3) the individual treatment programs vary. Lupus nephritis uneven, there are many types of different types should be taken to different treatment options.

(4) Note that prevention of complications. This point is often overlooked. Lupus nephritis patients during treatment is prone to a variety of complications, such as infection, cardiovascular complications, femoral head necrosis, severe cases can be life-threatening

Shijiazhuang Kidney Disease Hospital, Division of Rheumatology experts: What is the principle of treatment of lupus nephritis?

(1) For patients with systemic lupus erythematosus lupus nephritis, renal biopsy can be clearly pathological type of kidney damage. To guide clinical treatment and prognosis has a positive meaning, therefore, conditions should be kidney pathology.

  (2) associated with mild proteinuria and renal manifestations of patients, first with corticosteroids prednisone daily 0.5 ~ 1mg / kg, clinical symptoms and laboratory remission maintenance dose is gradually reduced to a minimum.

  (3) recurrence or renal pathological type of Ⅲ, Ⅳ, Ⅴ type of lupus nephritis, immunosuppression combined with corticosteroid therapy; for severe active lupus nephritis, such as pathology showed crescentic glomerulonephritis and / or fiber -like necrosis can be high-dose methylprednisolone pulse therapy.