Shijiazhuang kidney hospital treatment of lupus nephritis how medication

Shijiazhuang kidney hospital Common treatment of lupus nephritis include basic treatment and intensive treatment, then explore the indications from the administration about the treatment and medication strength of lupus nephritis.

A commonly used treatment

(1) Shijiazhuang kidney hospital  treatment of lupus nephritis basic treatment

Once established, a so-called basic treatment or diagnostic action to start using. Just use the basic treatment of hormone; 80 pairs of hormones on the basis of the application, advocate later, with other immunosuppressive agents the same time. You can choose steroids and cyclophosphamide, azathioprine, or hormones, because he mofetil or cyclosporine as: leflunomide and tacrolimus Division immune agents, clinical reports have been used in the treatment of lupus nephritis However, there are no signs, including its legal lupus nephritis.

(2)Shijiazhuang kidney hospital treatment of lupus nephritis intensive treatment

Severe in some patients require intensive treatment. Methylprednisolone, cyclophosphamide, plasmapheresis, plasma adsorption treatment belong to the category of intensive treatment.

(3)Other Treatment

If necessary, you can consider high-dose intravenous antibody injection or intravenous injection of anti-CD4 monoclonal antibody to correct abnormal immune lupus nephritis.

Second, drug indications and lupus nephritis

Current therapies in patients with lupus nephritis is different, but how reasonable the current treatment is still an important issue. To properly grasp the treatment of lupus nephritis therapeutic indications.

(A) basic treatment indications

1, hormones and cyclophosphamide or azathioprine

Cyclophosphamide basis hormone combination therapy is the most common. Cyclophosphamide in the 1970s, now used in most cytotoxic drugs. Rheumatoid larger dose cyclophosphamide, but Western countries believe that the application does not require much of cyclophosphamide certain accumulation, such as kidney disease is often controlled between 8 grams to 12 grams; then you can use azathioprine to maintain remission, the consolidation effect . Therefore, in combination with azathioprine hormones can be regarded as a control activities.

2, mycophenolate hormone combination

The combination hormone therapy? He phenol ester active disease indications renal lupus activity. 1997, Western countries began to use it with lupus and not with the treatment of lupus kidney disease is limited "V" and Ⅲ lupus nephritis, and later was used to treat type Ⅴ + Ⅳ and Ⅴ + Ⅲ type of lesion activity and lupus nephritis and achieved good results.

Connecting ring, hormone spore elements combined with cyclosporin, hormone therapy is indicated for patients with a combination of bone marrow suppression lupus activity (bone marrow biopsy confirmed) of.

Cyclospora no bone marrow suppression, in combination with CsA, especially for the treatment of lupus-related myelosuppression. Cyclophosphamide has a strong bone marrow suppression, while China will kill your white blood cells, side effects, azathioprine, although physical function mofetil 7 outside the lymphatic system is very small, but I saw it in the clinical difficult cure anemia, leukopenia, only cyclosporine drugs found no bone marrow suppression.

In theory, some patients can not use cytotoxic drugs, can be used as second-line drug cyclosporine. But it's the best indicator of bone marrow suppression combining lupus activity.