IgA Nephropathy: Symptoms and Prognosis

IgA Nephropathy

IgA Nephropathy is an autoimmune disease. It is characterized with the deposition of IgA deposition and other complex. In the western medicines, the patients mainly use hormone to restrain immunoreaction so as to decline the deposition of complex. Although the patients can receive a good therapeutic effect in a short time, it can not improve patients’ immunity at all. Therefore, once patients stop using hormone, their disease will reoccur again. In order to get a better therapeutic effect, the patients should receive relative treatment from the pathogenesis of IgA Nephropathy.
In many years’ clinical practices, traditional Chinese herb has an extraordinary effect in treating IgA Nephropathy. Through the following treating processes, the patients can get a good therapeutic effect.
1. Degrading immune complex
IgA Nephropathy is mainly characterized by the deposition of immune in the mesangial area. Traditional Chinese herb can degrade immune complex thus blocking their damage to the renal intrinsic cells.
2. Improve blood circulation
Mesangial cells control the contraction of blood capillaries. As the proliferation of mesangial cells, the blood capillaries will be contracted persistently. Therefore, the blood vessels lumina will become narrow, which can cause obstruction of blood circulation thus causing renal ischemia and anoxia.
Traditional Chinese herb can block the microcirculation disorder thus improve the renal ischemia and anoxia.
3. Anti-inflammatory effect
The depositions of immune complex can diffusive proliferative mesangial cells and obviously broadened mesangial area and glomerulosclerosis, which can initiate the kidney inflammatory response. Traditional Chinese medicine has an anti-inflammatory effect, which can eliminate the inflammatory factors so as to prevent the disease from developing further.
4. Improve immunity
Traditional Chinese medicines can improve patient’s immunity. Therefore, it can treat IgA Nephropathy from its fundamental cause.
Traditional Chinese medicines have an obvious effect in treating IgA Nephropathy, which brings much hope to all patients.
5. Repair damaged renal intrinsic cells
If the kidney can not get sufficient oxgen and blood supplement, it will initiate the fibrosis process of kidney. As a result, the renal intrinsic cells will lose their normal function and structures gradually.
Traditional Chinese medicines can improve renal ischemia and anoxia thus blocking fibrosis process. In addition, the medicines can provide some nutrition such as vitamin, trace elements, organic acid and so on.
The following factors can influence the prognosis of IgA Nephropathy.
* The prognosis of IgA Nephropathy is poorer in male than female. What’s more, the earlier the disease starts, the worse its prognosis will be.
* For the persons with frequent gross hematuria, the prognosis is bad.
* If the persons with IgA Nephropathy develop massive proteinuria or Nephrotic Syndrome, the prognosis is not good.
* If the persons with IgA Nephropathy have a poor control of blood pressure, the prognosis is bad.
* If the pathological change in IgA Nephropathy such as crescent formation, interstitial fibrosis etc, the prognosis is bad.