pay attention to the early diagnosis and treatment of kidney disease

chronic kidney disease

Diverse etiology of chronic kidney disease, for people with chronic kidney disease risk factors need our special attention, these risk factors include: diabetes, hypertension, autoimmune disease, systemic infection,> 60 years old, have a family history of kidney disease, acute renal failure and recovery and the like. Clinicians in these high-risk groups should conduct regular urine protein or microalbuminuria testing.
Early onset of chronic kidney disease often hidden, some patients may manifest as swelling, foamy urine, high blood pressure, when treatment is already a lot of young patients with advanced renal failure, lost the opportunity to reverse the treatment. And there is a considerable proportion of patients in clinical physical examination occasionally found hypertension, proteinuria, and renal insufficiency, so pay attention to the signals early in routine physical examination for early detection of kidney disease, kidney disease is important.

Treatment of chronic kidney disease

The main manifestations of chronic kidney disease include hypertension, proteinuria, hematuria and renal dysfunction. For patients with hypertension should be routine urine detection except renal hypertension, should periodically thereafter (per year) to review the early detection of microalbuminuria in hypertensive renal damage.

Proteinuria is an important prognostic indicator of kidney disease, clinical testing methods including urine, microalbuminuria, 24-hour urinary protein, urine protein electrophoresis, different detection methods have different sensitivities and characteristics, can delay the effective control of chronic proteinuria progression of renal disease and reduce cardiovascular complications.

For a long treatment of chronic kidney disease using serum creatinine to assess renal function, assessment of renal function with a serum creatinine but lack sufficient sensitivity. First, creatinine by age, race and gender influence, the same young men and creatinine levels of older women, their level of kidney function is completely different. Second, because the kidney has a strong compensatory function, renal dysfunction only when more than 50% increase in serum creatinine to appear, and most 3 chronic kidney disease (glomerular filtration rate in 30-60ml / min between ) in patients with serum creatinine levels are in the normal high is often not taken seriously.

With the proposed definition of Treatment of chronic kidney disease, we emphasize the correct assessment of renal function, the formula method to calculate the glomerular filtration rate, isotope detection, endogenous creatinine clearance measurement, iohexol (Iohexol) plasma clearance rate measurement, blood cystatin (CystatinC), etc. can be applied to the determination of the early assessment of renal dysfunction. Clinical generally recommended two to three kinds of comprehensive assessment method, for some special populations such as obesity, children, the elderly, patients need to pay attention to choose myopathy and other appropriate assessment tools.