Polycystic kidney disease (PKD) is a genetic disorder

Polycystic kidney disease

Polycystic kidney disease (PKD) is a genetic disorder
Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys.
Autosomal dominant PKD is the most common inherited form while autosomal recessive PKD is a rare.

When polycystic kidney disease causes numerous cysts to form in the kidneys, the kidneys get severely enlarged, and the cysts also take the place of normal kidney tissue. With less normal kidney tissue, the kidneys cannot function as well, and eventually the kidneys may fail. Cysts normally form in the kidneys as people age, but with polycystic kidney disease there are many more cysts than normal, and they cause problems in the body.

PKD Treatment is a leading cause of ESRD worldwide. In PKD, excessive cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with an abnormal extracellular matrix and alternatively activated interstitial macrophages

PKD Treatment is found on all continents and amongst all ethnic groups throughout the world. It is not known just how many people in Australia have the disease because symptoms often don't appear until later in life and many people do not know they have the disease. In Australia, PKD accounts for 6% of all people diagnosed with kidney failure. The approximate frequency of PKD in Caucasians is 1 in 400 to 1 in 1000. Because of its inheritance pattern, the children of PKD patients will have a 50% chance of inheriting the disorder.

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