Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure.
When PKD Treatment causes kidneys to fail--which usually happens only after many years--the patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease
The kidneys are two organs, each about the size of a fist, located in the upper part of a person’s abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. They also regulate amounts of certain vital substances in the body.
PKD can strike anyone at any time. About 5% of all people requiring dialysis or kidney transplantation have PKD.
PKD is an inherited disease. This means that it is passed on from parents to their children. Everyone has 23 different pairs of chromosomes, with one set coming from each parent. Chromosomes are scaffolds that carry individual hereditary units called genes. Genes are programmed to produce proteins. Proteins are the structural and functional building blocks that enable individual cells to work properly.
Kidney failure occurs when you are left with less than 10-15% of total kidney function. When the kidneys fail, PKD treatment or a kidney transplant is needed. Not everyone with PKD Treatment will go on to develop kidney failure.
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