What are the causes of Polycystic Kidney Disease

Polycystic kidney disease

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Polycystic kidney disease is a kidney cortex and medulla have multiple cysts of a hereditary kidney disease, due to gene mutations lead to some changes in renal interstitial cell growth and the formation of abnormal, which appears polycystic kidney disease. After the study and treatment of long-standing experience in the summary, the experts pointed out that the cause of polycystic kidney disease are manifold:

A congenital dysplasia: congenital dysplasia can produce a variety of diseases, for cystic kidney disease, the main cause medullary sponge kidney may be stunted polycystic kidney disease, congenital abnormalities of genes is generally no exception, so it and genetic mutations or there is a difference.

Second, a variety of infections: infection can change the body's internal environment abnormal, resulting in beneficial genes cyst changing environmental conditions, internal factors enhance the activity of the cyst, which can promote the growth of cysts, and any part of the body of any infection, in turn affecting the kidneys through the blood into the cyst, if the cyst infection, in addition to causing the clinical symptoms are aggravated, it will also promote further accelerate the growth rate of the cyst, and aggravation of renal impairment.
Third, the gene mutation (non-genetic): polycystic kidney disease mostly through genetic parents, divided into autosomal dominant and autosomal recessive inheritance, but also part of the hereditary polycystic kidney disease patients are neither parents nor belong to the innate dysplasia polycystic kidney disease, but mutations of the embryo formation. During embryogenesis, due to various factors that gene mutations and the formation of polycystic kidney disease.
Fourth, the toxins: toxin in the human body, can cause damage to various organs, cells and tissues, and thus disease, even life-threatening, and also produce mutations, one of the major congenital abnormalities such phenomena.
These are on the "cause of polycystic kidney disease," the talks, hoping to help a friend of the patient, the disease can be done in the event of early detection and early treatment.